Evaluation of Our Clinic Data on LAH

While the cited study above is well written, we also want to see if our clinic data matches these findings. We can look at our last 293 non-PGT tested embryo transfers consisting of 319 embryos. This represents 26 double embryo transfers and 267 single embryo transfers (91% single embryo transfer rate). The average patient age was 31 years old at the time of oocyte retrieval. 86 of 293 transfers used laser assisted hatching (29%). We take expected rates of live birth from the “Embryo morphology and live birth in the United States” manuscript. The expected rate of fetal heartbeat is defined as the live birth rate divided by 0.93. So a live birth rate of 40% equates to an expected heartbeat rate of 43%. We look at the heartbeat rate because for much of our recent dataset live birth has not yet occurred.

Our results are in agreement with the larger published study finding no positive or negative effect of last assisted hatching for frozen embryo transfers.

Awadalla MS, Ho JR, McGinnis LK, Ahmady A, Cortessis VK, Paulson RJ. Embryo morphology and live birth in the United States. F&S Reports. 2022 Jun 1;3(2):131-7.